top of page

Can Stress Affect Your Period and Fertility? The Science Behind the Effects of Stress on the Menstrual Cycle



girl sitting at desk in front of laptop holding her temples due to a stress headache

As a female physician with a special interest in reproductive health and natural family planning, I've seen firsthand how stress can affect your period. Today, I want to delve into how stress can impact menstruation and fertility, backed by scientific studies and medical journals.


Stress, whether physical, emotional, or psychological, can significantly disrupt the delicate hormonal balance required for regular ovulation and menstrual cycles. Let's explore how stress can lead to changes in the menstrual cycle through delayed ovulation, prolonged luteal phases, and altered levels of critical hormones like progesterone and estrogen, and take a look at the mechanisms behind these impacts.




Mechanisms Behind Stress's Impact on Hormone Levels

The relationship between stress and reproductive function is mediated by complex hormonal pathways, primarily involving cortisol, the body's primary stress hormone. Typically, as stress rises, cortisol will increase while progesterone and other reproductive hormones decrease. Elevated cortisol levels due to acute or chronic stress can:

  • Inhibit GnRH Release: GnRH (gonadotropin-releasing hormone) is crucial for initiating the sequence of hormonal events that lead to ovulation. Stress activates the body's fight or flight response, leading to the release of cortisol and adrenaline. These hormones can inhibit the secretion of gonadotropin-releasing hormone (GnRH), which is essential for the start of the ovulatory cycle.

  • Alter LH and FSH Levels: LH (luteinizing hormone) and FSH (follicle-stimulating hormone) are directly involved in stimulating the ovaries to produce and release eggs. Stress can lead to imbalances in these hormones, further complicating ovulation and menstrual regularity. A study published in "Stress" demonstrates that acute psychological stress can significantly reduce luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels, leading to delayed or even inhibited ovulation (Ferin, 1999).

  • Impact Progesterone and Estrogen Production: The ovaries' ability to produce these vital hormones can be compromised under stress, affecting everything from the thickening of the uterine lining to the timing and quality of ovulation. Progesterone is crucial for preparing the endometrium for potential pregnancy, while estrogen regulates the menstrual cycle and prepares the egg for ovulation. Stress can lead to lower progesterone levels, diminishing the chances of implantation and pregnancy. Additionally, stress-induced changes in estrogen levels can lead to irregular menstrual cycles, affecting overall fertility. The "Journal of Clinical Endocrinology & Metabolism" provides insight into how psychological stress affects these hormonal levels, influencing reproductive health (Whirledge & Cidlowski, 2010).




How Stress Can Affect Your Period and Overall Menstrual Cycle

  • Delayed Ovulation and Prolonged Follicular Phase:  Stress has been shown to impact the HPG (hypothalamic-pituitary-gonadal) axis. In a normal cycle, the hypothalamus releases GnRH (gonadotropin releasing hormone), which triggers the pituitary gland to release FSH (follicle stimulating hormone) to lead to maturation and development of an egg, and LH (luteinizing hormone), which causes the release of that egg. This egg can become fertilized by sperm leading to conception. However, stress can inhibit the release of GnRH, leading to the inhibiting of the production of other reproductive hormones. If the LH surge never occurs or is delayed, you will see a prolonged follicular phase (first half of your cycle) and delayed ovulation. Additionally, if FSH is not released, than no follicle can grow and be released for ovulation to occur, therefore causing an anovulatory cycle.

  • Shortened Luteal Phase: When GnRH is inhibited due to stress, this can also inhibit the production of progesterone. Progesterone is the hormone that is responsible for the second half of the menstrual cycle, known as the luteal phase. Decreased progesterone levels lead to a shorter luteal phase, which normally can last anywhere between 11-17 days.

  • Amenorrhea: Stress can lead to the absence of menstruation entirely, known as amenorrhea. This condition arises when heightened levels of stress hormones interfere with the hypothalamic-pituitary-gonadal axis (HPG axis), leading to a suppression of the hormonal signals necessary for ovulation and menstruation.

  • Menstrual Irregularity: Even if menstruation continues, stress can cause cycles to become more erratic in length, flow, and symptomatology. For some, this might mean unexpectedly short or unusually long cycles; for others, it could result in heavier or lighter periods than usual.

  • Anovulation: Stress doesn't always stop menstruation altogether but can lead to anovulatory cycles, where no ovulation occurs. This situation can be particularly frustrating for individuals tracking their cycles for natural family planning, as it introduces unpredictability and challenges in fertility tracking.



Click here for the blog article regarding more information on what is considered an irregular cycle and abnormal luteal phase length.


To read my blog post about understanding the basics of the menstrual and ovulatory cycles, click here.



The Importance of Identifying Menstrual Cycle Changes for Improved Fertility

When significant changes happen in the menstrual and ovulatory cycles, this can lead to issues with fertility and getting pregnant. It can either cause a delay in ovulation, which can make timing of intercourse for conception extremely challenging. Additionally, it can cause anovulation altogether. If no egg is being matured and released from the ovaries each menstrual cycle, then no fertilization of the egg can occur at all. Finally, progesterone is the reproductive hormone that helps maintain a pregnancy and make the uterine lining favorable for implantation. If progesterone is low due to stress, it is much more challenging for a fertilized egg to be able to implant in the uterus, which can increase chances of miscarriage.


Therefore, even if you don't feel as if you are stressed, make sure to be looking out for signs within your cycle charting that could identify cycle irregularities possibly caused by stress.  These signs include a prolonged follicular phase (time from the start of your period until ovulation lasting longer than 21 days), no ovulation occurring (marked by no rise in BBT or progesterone level), or a shortened luteal phase (the time between ovulation and the start of your next period lasting less than 11 days).





a relaxing bubble bath with Epsom salts, a burning candle, and a bath bomb

Addressing Stress and Fertility

Given the substantial impact stress can have on the menstrual cycle and ovulation, addressing stress becomes a pivotal part of managing reproductive health. Strategies for managing stress and supporting the reproductive system include:

  • Lifestyle Modifications: Incorporating regular physical activity, ensuring adequate sleep, and adopting a balanced diet can all help mitigate the effects of stress on the body.

  • Psychological Support: Therapy, counseling, and stress-reduction techniques like mindfulness and prayer can provide effective tools for managing psychological stress and its physiological repercussions.

  • Medical Interventions: In some cases, medical treatment may be necessary to address the disruptions caused by stress. This could include hormonal therapies to regulate the menstrual cycle or tailored approaches to manage specific conditions like amenorrhea or anovulation. Additionally, it could include different medications or supplements to help decrease anxiety and stress. One supplement I would recommend trying for stress relief is OLLY Ultra Strength Goodbye Stress capsules. However, I would advise only taking these while trying to manage stress and fertility, but then discontinuing these supplements once you are pregnant since not all of its ingredients have had adequate safety testing done on pregnant women. Additionally, supplementing with Magnesium and Fish Oil have also been shown to decrease stress.


Click here to read my blog article about different lifestyle changes you can make to improve stress and fertility, which includes relaxation methods, different foods to incorporate into your diet, and helpful exercises to try in your fitness routine.




Conclusion

In summary, as we navigate the complexities of stress and its impact on fertility, it's clear that addressing stress is not just about improving mental health—it's a crucial component of reproductive health. The effects of stress on the menstrual cycle and ovulation are profound and multifaceted, impacting not just the regularity of cycles but the very ability to conceive. Understanding these impacts are crucial for anyone navigating the challenges of reproductive health. By incorporating stress-reduction strategies into our daily lives and seeking professional support when needed, we can create a more favorable environment for conception and overall reproductive health.




References:

Ferin M. (1999). Clinical review 105: Stress and the reproductive cycle. The Journal of clinical endocrinology and metabolism, 84(6), 1768–1774. https://doi.org/10.1210/jcem.84.6.5367


Whirledge, S., & Cidlowski, J. A. (2010). Glucocorticoids, stress, and fertility. Minerva endocrinologica, 35(2), 109–125.


Σχόλια


bottom of page